Job 22:5

For thou hast taken a pledge from thy brother for nought,.... It can hardly be thought that it was for nothing at all, on no consideration whatever, or that nothing was lent, for which the pledge was…

Is not thy wickedness great? - That is, “Is it not utter presumption and folly for a man, whose wickedness is undoubtedly so great, to presume to enter into a litigation with God?” Eliphaz here…

Eliphaz and his companions had condemned Job, in general, as a wicked man and a hypocrite; but none of them had descended to particulars, nor drawn up any articles of impeachment against him, until…

Job's afflictions are because of his sins sins which Eliphaz now suggests and enumerates. They are such sins as a powerful Oriental ruler naturally falls into, inhumanity, avarice, and abuse of power.